This test requires only a blood or hair root sample. Such a check is suggested when, for instance, a horse reveals indicators of PSSM or when blood work reveals increased muscle enzyme activity that can not be defined by physical effort. Testing can be essential for stallions and mares used in breeding if the genetic defect is frequent in the breed. This includes Quarter Horses, Paint Horses, many draught breeds, Haflingers, and Cobs. Affected horses shouldn't be used for breeding functions. Not all horses displaying indicators of PSSM test optimistic in genetic exams. If a horse has recurring acute muscular problems however no mutation of the GYS1 gene, the horse proprietor learn more is initially introduced with a puzzle. What now? The horse appears sick and all the pieces factors to PSSM, however the horse just isn't a provider of the mutated GYS1 gene. Meanwhile, there are now different genetic checks offered on the market. However, it should be emphasised that these exams have not yet been validated and the current scientific data means that they aren't suitable for diagnosing Type 2 PSSM.

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Archives of Medicine and Health Sciences. OMIM - Online Medelian Inheritance in Man. Kishnani, Priya S.